منابع مشابه
The intriguing plant nuclear lamina
The nuclear lamina is a complex protein mesh attached to the inner nuclear membrane (INM), which is also associated with nuclear pore complexes. It provides mechanical support to the nucleus and nuclear envelope, and as well as facilitating the connection of the nucleoskeleton to the cytoskeleton, it is also involved in chromatin organization, gene regulation, and signaling. In metazoans, the n...
متن کاملNuclear envelope, nuclear lamina, and inherited disease.
The nuclear envelope is composed of the nuclear membranes, nuclear lamina, and nuclear pore complexes. In recent years, mutations in nuclear-envelope proteins have been shown to cause a surprisingly wide array of inherited diseases. While the mutant proteins are generally expressed in most or all differentiated somatic cells, many mutations cause fairly tissue-specific disorders. Perhaps the mo...
متن کاملThe isolation of the nuclear lamina
The isolation of the nuclear lamina he number of monikers early cell biologists attached to the nuclear lamina reflected their uncertainty about its function and architecture, and whether it was widespread or confined to a few specialized cells. Electron micrographs often disclosed a layer of varying thickness nestled against the backside of the nuclear membrane, which various researchers dubbe...
متن کاملStochastic genome-nuclear lamina interactions
The nuclear lamina (NL) is thought to aid in the spatial organization of interphase chromosomes by providing an anchoring platform for hundreds of large genomic regions named lamina associated domains (LADs). Recently, a new live-cell imaging approach demonstrated directly that LAD-NL interactions are dynamic and in part stochastic. Here we discuss implications of these new findings and introdu...
متن کاملThe nuclear lamina during human spermiogenesis
The nuclear lamina takes centre stage during spermiogenesis, the post-meiotic phase of spermatogenesis, when haploid round spermatids differentiate into spermatozoa: the acrosome and flagellum develop at opposite nuclear poles, the nucleus elongates and, as the nuclear histones are replaced with protamines, the chromatin condenses, to produce the highly compacted pyriform nucleus of the mature ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: FEBS Journal
سال: 2007
ISSN: 1742-464X
DOI: 10.1111/j.1742-4658.2007.05694.x